We are an academic research laboratory in the School of Pharmacy at the University of Reading, (Reading, Berkshire, UK) studying adult stem cell biology as well as in the influence of injury and inflammation on somatic cells. We want to understand how inflammatory signalling pathways influence (de-) differentiation, proliferation, and migration of different (stem) cell types.

Darius Widera

Widera lab 2019

In addition, we work on human, ovine, and murine neural crest-derived stem cells and mesenchymal stem cells/marrow stromal cells and their secretome and develop 3D cell culture systems.

Visualisation of our pubmed-listed abstracts generated using the Wordle.net algorithm.

We further apply modern microscopy methods to address the stimulus-dependent behaviour of receptors (especially tumor necrosis receptor I and Toll-like receptor 4) and the resulting downstream signalling in stem cells and cancer (tumour) stem cells.

Finally, our lab is developing novel stem cell-based, cell-free therapies for degenerative disorders and conditions.

We are actively searching for industrial partners to commercialise our research and ideas. For details on our research please visit the Research and Publications sections.

 Darius Widera

Widera lab 2018


Darius Widera

Widera lab 2017

Funding (current and past):


 UPM Kymmene

Marie Curie Actions