We are an academic research laboratory in the School of Pharmacy at the University of Reading, (Reading, Berkshire, UK) interested in adult stem cells as well as in the influence of injury and inflammation on somatic cells. We want to understand how inflammatory signalling pathways influence (de-) differentiation, proliferation, and migration of different (stem) cell types.

Widera lab 2017

In addition, we work on novel human, ovine, and murine neural crest-derived stem cell populations, which are promising candidates for the development of autologous cell-based therapies in the context of regenerative medicine.

Visualisation of our pubmed-listed abstracts generated using the Wordle.net algorithm.

We further apply modern microscopy methods to address stimulus-dependent behaviour of receptors (especially tumor necrosis receptor I and Toll-like receptor 4) and the resulting downstream signalling in stem cells and cancer (tumour) stem cells.

Finally, our lab is developing novel stem cell-based, cell-free therapies for degenerative disorders and conditions.

We are actively searching for industrial partners to commercialise our research and ideas. For details on our research please visit the Research and Publications sections.

 

Our research is currently funded by start-up funds of the University of Reading, the German Research Foundation (DFG), the Saudi Government, and the British Heart Foundation.