We are an academic research laboratory in the School of Pharmacy at the University of Reading, (Reading, Berkshire, UK) interested in adult stem cells as well as in the influence of injury and inflammation on somatic cells. We want to understand how inflammatory signalling pathways influence (de-) differentiation, proliferation, and migration of different (stem) cell types.

Widera lab 2018

In addition, we work on human, ovine, and murine neural crest-derived stem cells and mesenchymal stem cells/marrow stromal cells and their secretome.

Visualisation of our pubmed-listed abstracts generated using the Wordle.net algorithm.

We further apply modern microscopy methods to address the stimulus-dependent behaviour of receptors (especially tumor necrosis receptor I and Toll-like receptor 4) and the resulting downstream signalling in stem cells and cancer (tumour) stem cells.

Finally, our lab is developing novel stem cell-based, cell-free therapies for degenerative disorders and conditions and work on 3D cell culture systems for somatic cells and stem cells.

We are actively searching for industrial partners to commercialise our research and ideas. For details on our research please visit the Research and Publications sections.

 

Widera lab 2017

Our research is currently funded by start-up funds of the University of Reading, the German Research Foundation (DFG), the Saudi Government, UPM Kymene, and the British Heart Foundation.