We are an academic research laboratory in the School of Pharmacy at the University of Reading, (Reading, Berkshire, UK) interested in adult stem cell research as well as in the influence of injury and inflammation on somatic cells (injury-induced cellular reprogramming). We want to understand how inflammatory signalling pathways influence (de-) differentiation, proliferation and migration of different (stem) cell types.
In addition, we work on novel human and murine neural crest-derived stem cell populations, which are promising candidates for the development of autologous cell-based therapies in the context of regenerative medicine.
Visualisation of our pubmed-listed abstracts generated using the Wordle.net algorithm.
We further apply modern microscopy methods to address stimulus-dependent behavior of receptors (especially tumor necrosis receptor I and Toll-like receptor 4) and the resulting downstream signalling in stem cells and cancer (tumour) stem cells.
We are actively searching for industrial partners to commercialise our research and ideas. For details on our research please visit the Research and Publications sections.
Our research is currently founded by start-up funds of the University of Reading and the German Research Foundation (DFG).